A-MYB (MYBL1) transcription factor is a master regulator of male meiosis
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چکیده
منابع مشابه
A-MYB (MYBL1) transcription factor is a master regulator of male meiosis.
The transcriptional regulation of mammalian meiosis is poorly characterized, owing to few genetic and ex vivo models. From a genetic screen, we identify the transcription factor MYBL1 as a male-specific master regulator of several crucial meiotic processes. Spermatocytes bearing a novel separation-of-function allele (Mybl1(repro9)) had subtle defects in autosome synapsis in pachynema, a high in...
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ژورنال
عنوان ژورنال: Development
سال: 2011
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.067645